METHOD OF OBTAINING RECOMBINANT POLYPEPTIIDE-ANTAGONIST OF SOMATOTROPIC HORMONE WITH REDUCED CONTENT OF ISOFORM ADMIXTURES (VERSIONS)

METHOD OF OBTAINING RECOMBINANT POLYPEPTIIDE-ANTAGONIST OF SOMATOTROPIC HORMONE WITH REDUCED CONTENT OF ISOFORM ADMIXTURES (VERSIONS)

FIELD: chemistry. ^ SUBSTANCE: invention relates to biotechnology. Method versions lie in fact that trisulfide isoform is brought into contact with mercaptocompound, either with chelating agent or with metal salt. ^ EFFECT: obtaining polypeptide product with reduced amount of trisulfide isoform admi...

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Bibliographische Detailangaben
Hauptverfasser: DZHONSON GEHRI V, ALLEN SKOTT I, BOJL DENNIS M, BAKLI DZHON DZH, RATOR ANURAG S, STEJNMAJER DEJVID I, MAJER DZHON, LAJL STIVEN B
Format: Patent
Sprache:eng ; rus
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Zusammenfassung:FIELD: chemistry. ^ SUBSTANCE: invention relates to biotechnology. Method versions lie in fact that trisulfide isoform is brought into contact with mercaptocompound, either with chelating agent or with metal salt. ^ EFFECT: obtaining polypeptide product with reduced amount of trisulfide isoform admixtures. ^ 30 cl, 5 dwg, 7 ex