WATER-SOLUBLE POLYMER COMPLEXES OF AMINOGLYCOSIDE ANTIBIOTICS

FIELD: chemistry. ^ SUBSTANCE: invention claims water-soluble polymer complexes of aminoglycoside antibiotics of the general formula: where AG is aminoglycoside antibiotic (base); m1=(100-m2) mol %; m2=17-1.9 mol %; with MM 20000-29000 ""; AG content of 13.0-17.2 wt %. Aminoglycoside antib...

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Hauptverfasser: EROPKIN MIKHAIL JUR'EVICH, GAVRILOVA IRINA IOSIFOVNA, KISELEV OLEG IVANOVICH, EROPKINA ELENA MIKHAJLOVNA, SOLOVSKIJ MIKHAIL VASIL'EVICH, PANARIN EVGENIJ FEDOROVICH, SHUL'TSEVA ELIZAVETA LEONIDOVNA
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: chemistry. ^ SUBSTANCE: invention claims water-soluble polymer complexes of aminoglycoside antibiotics of the general formula: where AG is aminoglycoside antibiotic (base); m1=(100-m2) mol %; m2=17-1.9 mol %; with MM 20000-29000 ""; AG content of 13.0-17.2 wt %. Aminoglycoside antibiotic is selected out of a group including gentamycin, kanamycin, neomycin. ^ EFFECT: reduced antibiotic toxicity. ^ 2 cl, 9 ex, 2 tbl, 3 dwg