APPLICATION OF PERFLUORALKYL-CONTAINIG METAL COMPLEX AS CONTRAST MEDIUM TO VISUALISE INTRAVASCULAR THROMBI DURING MAGNETIC RESONANCE IMAGING

FIELD: medicine; pharmacology. ^ SUBSTANCE: invention concerns application of perfluoralkyl-containing metal complex characterised by critically concentrated micelle formation less 10-3 moles/l, hydrodynamic micelle diameter (2Rh) more than 1 nm and proton relaxation in plasma (R1) more than 10 l/mm...

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Hauptverfasser: KAVATA EKO, NIDBALLA UL'RIKH, PLATTSEK IOGANNES, EKAVA TAKISHI, MISSEL'VITTS BERND, VAJNMANN KHANS-JOAKHIM
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine; pharmacology. ^ SUBSTANCE: invention concerns application of perfluoralkyl-containing metal complex characterised by critically concentrated micelle formation less 10-3 moles/l, hydrodynamic micelle diameter (2Rh) more than 1 nm and proton relaxation in plasma (R1) more than 10 l/mmole-sec, as contrast medium applied to visualise intravascular thrombi during magnetic resonance imaging (MRI). ^ EFFECT: extended range of agents used as contrast medium for magnetic resonance imaging. ^ 50 cl, 7 dwg, 1 tbl, 7 ex