DERIVATIVES OF 1-N-PHENYLAMINO-1H-IMIDAZOLE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

DERIVATIVES OF 1-N-PHENYLAMINO-1H-IMIDAZOLE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

FIELD: chemistry; pharmaceutical compositions. ^ SUBSTANCE: imidazole derivatives have general formula (I) where each of R1 and R2 independently represents hydrogen, (C1-C6)alkyl or (C3-C8)cycloalkyl; n=0.1 or 2; each of R3, R4, R5 and R6 independently represents hydrogen or (C1-C6)alkyl, halogen, c...

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Bibliographische Detailangaben
Hauptverfasser: KARNIATO DENI, PASKAL' ZHAN-KLOD, BONNE POL, DELANSORN REMI, LAFAJ ZHAN, ADZHE NATALI
Format: Patent
Sprache:eng ; rus
Schlagworte:
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMISTRY
FISHING
FORESTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TRAPPING
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Beschreibung
Zusammenfassung:FIELD: chemistry; pharmaceutical compositions. ^ SUBSTANCE: imidazole derivatives have general formula (I) where each of R1 and R2 independently represents hydrogen, (C1-C6)alkyl or (C3-C8)cycloalkyl; n=0.1 or 2; each of R3, R4, R5 and R6 independently represents hydrogen or (C1-C6)alkyl, halogen, cyano, (C1-C6)alkoxy, trifluoromethyl, (C1-C6)alkylthio, (C1-C6)alkylsulphonyl or (C1-C6)alkoxycarbonyl; R3 and R6 together with their carrier phenyl ring can also form N-methylbenzotriazole and to its acidic-additive salts, solvates and stereoisomer forms. Also, the given invention relates to pharmaceutical compositions, inhibitory aromatiser and application of derived imidazole of formula (I) for producing of medication. ^ EFFECT: new compounds, with useful biological properties. ^ 23 cl, 2 tbl, 33 ex