4-PYPERAZINYL-BENZEN-SULFANYLINDOLES WITH AFFINITY TO 5-HT6 RECEPTOR

FIELD: medicine; pharmacology. ^ SUBSTANCE: invention is related to 4-pyperazinyl-benzen-sulfanylindols with the general formula I , where: R1 and R2 each independently means hydrogen, halogen, alcoxy, R3 and R4 each independently means hydrogen, halogen, alkyl, n is equal to 0 to 4, R6 in each part...

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Hauptverfasser: KHARRIS RALF N'JU III, KLARK ROBIN DUGLAS, REPKE DEJVID BRJUS
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine; pharmacology. ^ SUBSTANCE: invention is related to 4-pyperazinyl-benzen-sulfanylindols with the general formula I , where: R1 and R2 each independently means hydrogen, halogen, alcoxy, R3 and R4 each independently means hydrogen, halogen, alkyl, n is equal to 0 to 4, R6 in each particular case means hydrogen or halogen, R7 and R8 each means hydrogen, R9 means hydrogen, alkyl, or individual isomer, racemic or non-racemic mixture of isomers or their pharmaceutically acceptable salt or solvate. The pharmaceutical compositions are described based on compound I. ^ EFFECT: compounds can be efficiently used in treatment of certain diseases of central nervous system. ^ 14 cl, 1 tbl, 4 ex