METHOD FOR PREDICTING ORGANISM RESISTANCE TO STRESS ACTION

FIELD: medicine. ^ SUBSTANCE: method involves taking peripheral patient blood to produce leukocyte suspension. The suspension is incubated with cAMP-phosphodiesterase inhibitor and without the inhibitor. Luminol-dependent chemiluminescence reaction curves are recorded and stimulation index (SI) is c...

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Hauptverfasser:	ONISHCHENKO NINA ANDREEVNA, TEMNOV ANDREJ ALEKSANDROVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	FIELD: medicine. ^ SUBSTANCE: method involves taking peripheral patient blood to produce leukocyte suspension. The suspension is incubated with cAMP-phosphodiesterase inhibitor and without the inhibitor. Luminol-dependent chemiluminescence reaction curves are recorded and stimulation index (SI) is calculated from formula: SI= Sinh/Sctr, where Sinh is the chemiluminescence reaction cells intensity in sample with cAMP-phosphodiesterase inhibitor, Sctr is the chemiluminescence reaction cells intensity in sample without the inhibitor. IS being >=0.6, the organism is considered to possess stable resistance to stress action, otherwise the organism shows stress resistance instability. ^ EFFECT: high accuracy of prognosis, in particular, when predicting severe postoperative complications. ^ 3 cl, 4 dwg, 4 tbl