USE OF ANTIBIOTICS AS VACCINE ADJUVANTS

FIELD: medicine, chemical-pharmaceutical industry, microbiology, pharmacy. ^ SUBSTANCE: invention relates to an adjuvant composition comprising antibacterial agent azalid tulathromycin wherein azalid acts as adjuvant. Also, invention relates to vaccine comprising some components and involving: (A) at least one antigen wherein antigen is chosen from group consisting of M. haemolytica antigen, M. haemolytica leukotoxin, M. haemolytica capsule antigen, M. haemolytica soluble antigen, or their mixture, and (b) at least one azalid, for example, tulathromycin wherein azalid acts as adjuvant. Adjuvant or vaccine compositions are used for prophylaxis and treatment of diseases caused by pathogenic factor, cancer cell or allergen in animal but not in human. Proposed adjuvant provides enhancing effectiveness of the vaccine composition. ^ EFFECT: improved and valuable medicinal properties of composition. ^ 10 cl, 16 tbl, 2 dwg, 5 ex