USE OF 2-ALKOXYPHENYL-SUBSTITUTED IMIDAZOTRIAZINONE

FIELD: organic chemistry, medicine, biochemistry pharmacy. ^ SUBSTANCE: invention relates to using the known 2-phenyl-substituted imidazotriazinone of the formula (I): (vardenafil) possessing improved properties as compared with other known inhibitors of phosphodiesterase-5 (PDE-5), such as sildenaf...

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Hauptverfasser: RAKHBAR AFSSANEKH, BANDEL' TIEMO-JORG, BISHOFF EHRVIN, NIVENER UL'RIKH, KHANING KHEL'MUT, BART VOL'FGANG
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: organic chemistry, medicine, biochemistry pharmacy. ^ SUBSTANCE: invention relates to using the known 2-phenyl-substituted imidazotriazinone of the formula (I): (vardenafil) possessing improved properties as compared with other known inhibitors of phosphodiesterase-5 (PDE-5), such as sildenafil and tadalafil. Proposed compound is used for preparing drugs used in treatment of cardiac insufficiency. ^ EFFECT: valuable medicinal and biochemical properties of compound. ^ 1 tbl