METHOD FOR PROPHYLAXIS OF RELAPSE LITHIASIS

FIELD: medicine. ^ SUBSTANCE: method involves administration of hyaluronidase conjugate (lydazum) with activated derivative of poly-1,4-ethylenepiperazine N-oxide (analog of polyoxidonium) in a single dose 3000 IU by intramuscular route, 3 days before of operative removal of concrements. After remov...

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Hauptverfasser: SKRJABIN GENNADIJ NIKOLAEVICH, TRUBNIKOVA KSENIJA EVGEN'EVNA, SAAD EHLIAS INAAM, BAREEVA ROZA SIBAGATOVNA, NAZAROV TOIRKHON KHAKNAZAROVICH, TIKTINSKIJ OLEG LEONIDOVICH, PASTUSHENKOV VLADIMIR LEONIDOVICH, KARPISHCHEKO ANATOLIJ IVANOVICH, ALEKSANDROV VALERIJ PAVLOVICH, MIKHAJLICHENKO VLADIMIR VASIL'EVICH
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine. ^ SUBSTANCE: method involves administration of hyaluronidase conjugate (lydazum) with activated derivative of poly-1,4-ethylenepiperazine N-oxide (analog of polyoxidonium) in a single dose 3000 IU by intramuscular route, 3 days before of operative removal of concrements. After removal of concrements the drug is administrated in indicated dose by the following schedule - once for 3 days, 5 injections, then once for 5 days, 15 injections, then once for 10 days, 15 injections. Proposed invention provides improvement and normalization of physicochemical and biochemical indices of urine that promotes to decreasing of relapse lithiasis. ^ EFFECT: improved method of prophylaxis. ^ 1 tbl, 1 ex