ANTIBACTERIAL PHARMACEUTICAL COMPOSITION POSSESSING PROLONGED EFFECT

FIELD: organic chemistry, medicine, pharmacology, pharmacy. ^ SUBSTANCE: invention relates to an antibacterial composition representing a complex of polyvinylpyrrolidone and metronidazol of the formula (I) wherein n = 76-276; m = 5-40, and containing 9-19% of metronidazol. Also, the invention relate...

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Bibliographische Detailangaben
Hauptverfasser:	FADEEVA TAT'JANA VLADIMIROVNA, GRIGOR'EV EVGENIJ GEORGIEVICH, KOGAN ALEKSANDR SEMENOVICH, ANTONIK LIDIJA MAKAROVNA, KUZNETSOVA EHMMA EHFROIMOVNA, KHABIBULINA AL'FIJA GALIMULLOVNA, LOPYREV VLADIMIR ALEKSANDROVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, medicine, pharmacology, pharmacy. ^ SUBSTANCE: invention relates to an antibacterial composition representing a complex of polyvinylpyrrolidone and metronidazol of the formula (I) wherein n = 76-276; m = 5-40, and containing 9-19% of metronidazol. Also, the invention relates to a method for preparing the indicated complex. The proposed composition provides maintaining the concentration of metronidazol at the therapeutic level for 48 h. ^ EFFECT: improved and valuable medicinal and pharmaceutical properties of composition. ^ 3 cl, 5 tbl, 5 ex