METHOD FOR INDOLE PRODUCTION
FIELD: organic chemistry. ^ SUBSTANCE: claimed method includes catalytic dehydration of commercial 4,5,6,7-tetrahydroindole with 0.1-5.0 % nickel sulfide, carried on alumina, at 250-400C in solvent in presence or absence of inert gas. Yield of target product is 92-96 % and selectivity is 100 %. ^ EF...
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Zusammenfassung: | FIELD: organic chemistry. ^ SUBSTANCE: claimed method includes catalytic dehydration of commercial 4,5,6,7-tetrahydroindole with 0.1-5.0 % nickel sulfide, carried on alumina, at 250-400C in solvent in presence or absence of inert gas. Yield of target product is 92-96 % and selectivity is 100 %. ^ EFFECT: method of high yield and selectivity. ^ 3 cl, 9 ex |
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