INFLUENZA VIRUS STRAIN FOR LIVING INFLUENZA INTRANASAL VACCINE FOR INFANTS AND ADULTS

FIELD: virology, immunology. ^ SUBSTANCE: vaccine strain reassortant is obtained by specific epidemic virus with cold-adapted temperature-sensitive virus as attenuation donor. Strain actively multiplies in developing hen embryos at optimal temperature of 32-33°C and is characterized with cold-adapta...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	RUDENKO LARISA GEORGIEVNA, LARIONOVA NATAL'JA VALENTINOVNA, KLIMOV ALEKSANDR IVANOVICH, ALEKSANDROVA GALINA IBRAGIMOVNA
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	FIELD: virology, immunology. ^ SUBSTANCE: vaccine strain reassortant is obtained by specific epidemic virus with cold-adapted temperature-sensitive virus as attenuation donor. Strain actively multiplies in developing hen embryos at optimal temperature of 32-33°C and is characterized with cold-adaptation and temperature-sensitivity. Strain has two genes from epidemic virus encoding surface proteins (hemagglutinin and neuroaminidase) and six genes from attenuation donor encoding internal non-glycosylated proteins. ^ EFFECT: new strain for living influenza intranasal vaccine for infants and adults. ^ 1 dwg, 3 tbl, 2 ex