METHOD FOR PREDICTING RAPID DISEASE PROGRESS IN HIV-INFECTED PATIENTS

METHOD FOR PREDICTING RAPID DISEASE PROGRESS IN HIV-INFECTED PATIENTS

FIELD: medicine, laboratory diagnostics. ^ SUBSTANCE: in patients in the stages of generalized lymphoadenopathy (GLAP) or pre-AIDS it is necessary to sample venous blood to detect quantitative content of CD+-, CD8+-, CD16+-, CD20+-lymphocytes and circulating immune complexes (CIC). In case of detect...

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Hauptverfasser: AMBALOV JURIJ MIKHAJLOVICH, SIZJAKINA LJUDMILA PETROVNA, PEREPECHAJ SVETLANA DMITRIEVNA
Format: Patent
Sprache:eng ; rus
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Zusammenfassung:FIELD: medicine, laboratory diagnostics. ^ SUBSTANCE: in patients in the stages of generalized lymphoadenopathy (GLAP) or pre-AIDS it is necessary to sample venous blood to detect quantitative content of CD+-, CD8+-, CD16+-, CD20+-lymphocytes and circulating immune complexes (CIC). In case of detecting during GLAP stage the quantity of CD4+- being below 0.46x10*9/l, CD20+ - above 0.095x10*9/l and CIC being above 170 c.u. at probability of 99.0% one should predict rapid disease progress. In case of detecting during pre-AIDS stage the quantity of CD8+ - above 0.11x10*9/l at probability of 95.5% it is, also, possible to predict rapid disease progress. The innovation enables to develop simple and available method for predicting rapid flow of HIV-infection. ^ EFFECT: higher accuracy of prediction. ^ 1 ex, 5 tbl