COMBINATION OF SPECIFIC OPIOIDS WITH MUSCARINE ANTAGONISTS FOR INCONTINENCE THERAPY

FIELD: pharmaceutical chemistry and urology. ^ SUBSTANCE: invention proposes treatment of frequent vesical tenesmus and incontinence with combination of tramadol, its derivatives, and derivatives of 1-phenyl-3-dimethylaminopropane compounds of formula I: with antimuscarine agents, in particular comb...

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1. Verfasser: KRISTOF TOMAS
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: pharmaceutical chemistry and urology. ^ SUBSTANCE: invention proposes treatment of frequent vesical tenesmus and incontinence with combination of tramadol, its derivatives, and derivatives of 1-phenyl-3-dimethylaminopropane compounds of formula I: with antimuscarine agents, in particular combination of (+)-(2R,3R)-1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentane-3-ol and oxybutynine. Invention also relates to drug form of this combination. ^ EFFECT: enlarged choice of incontinence treatment agents. ^ 2 cl, 1 tbl, 2 ex