COMPOUND AND METHOD OF PREPARATION THEREOF

FIELD: complexing compounds. ^ SUBSTANCE: invention provides macrocyclic metal complexes, preparation thereof, and application thereof to form conjugates with biomolecules. Such conjugates are appropriate for use as contrast substances in NMR diagnostics and for use in radiotherapy. ^ EFFECT: enhanc...

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Bibliographische Detailangaben
Hauptverfasser:	SHMITT-VILLIKH KHERIBERT, SHIRMER KHEJKO, VAJNMANN KHANNS-JOAKHIM, PLATTSEK IOGANNES, BAUER KHANS, MIKHL' GJUNTER, ZJUL'TSLE DETLEF, FRENTSEL' TOMAS, RADJUKHEL' BERND
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	FIELD: complexing compounds. ^ SUBSTANCE: invention provides macrocyclic metal complexes, preparation thereof, and application thereof to form conjugates with biomolecules. Such conjugates are appropriate for use as contrast substances in NMR diagnostics and for use in radiotherapy. ^ EFFECT: enhanced relaxation ability and possibility to control it due to special ligands attached to macrocycles. ^ 12 cl, 2 tbl, 91 ex