IMMUNOSTIMULATING G,U-CONTAINING OLYGORIBONUCLEOTIDES

FIELD: biology. ^ SUBSTANCE: invention relates to compositions containing immunostimulating RNA olygomers and uses thereof. Claimed molecules of immunostimulating RNA having chain length of 5-40 nucleotides and including at least one guanine and at least one uracyl have immunostimulating properties...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	LIPFORD GREHJSON B, VAGNER KHERMANN, BAUER SHTEFAN
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	FIELD: biology. ^ SUBSTANCE: invention relates to compositions containing immunostimulating RNA olygomers and uses thereof. Claimed molecules of immunostimulating RNA having chain length of 5-40 nucleotides and including at least one guanine and at least one uracyl have immunostimulating properties and represent exclusive ligands of one or more Toll-like receptors, including Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8). ^ EFFECT: composition and methods for stimulation of immune response activation. ^ 120 cl, 23 ex, 20 dwg