METHOD FOR PREPARING N-SUBSTITUTED DERIVATIVES OF 4,6-DIMETHYL-3-CYANOPYRIDYL-2-SULFONYLAMIDES

METHOD FOR PREPARING N-SUBSTITUTED DERIVATIVES OF 4,6-DIMETHYL-3-CYANOPYRIDYL-2-SULFONYLAMIDES

FIELD: organic chemistry, chemical technology. ^ SUBSTANCE: invention describes a method for synthesis of N-substituted derivatives of 4,5-dimethyl-3-cyanopyridyl-2-sulfonylamides that can be used as biologically active substances. Method involves preliminary synthesis of 4,6-dimethyl-3-cyanopyridyl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KAJGORODOVA ELENA ALEKSEEVNA, DJADJUCHENKO LJUDMILA VSEVOLODOVNA, STRELKOV VLADIMIR DENISOVICH, KONJUSHKIN LEONID DMITRIEVICH, DMITRIEVA IRINA GENNADIEVNA
Format: Patent
Sprache:eng ; rus
Schlagworte:
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMISTRY
FISHING
FORESTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HUNTING
METALLURGY
ORGANIC CHEMISTRY
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:FIELD: organic chemistry, chemical technology. ^ SUBSTANCE: invention describes a method for synthesis of N-substituted derivatives of 4,5-dimethyl-3-cyanopyridyl-2-sulfonylamides that can be used as biologically active substances. Method involves preliminary synthesis of 4,6-dimethyl-3-cyanopyridyl-2-sulfonyl chloride by oxidative chlorination of 4,6-dimethyl-3-cyano-(1H)-pyridyl-2-thione without drying step that is subjected for interaction with amine. Interaction with amines is carried out by addition of amine solution in acetone to aqueous suspension of 4,6-dimethyl-3-cyanopyridyl-2-sulfonyl chloride at temperature 8-10°C. Invention provides synthesis of end substances with high yields - 69-74%. N-substituted derivatives of 4,6-dimethyl-3-cyanopyridyl-2-sulfonylamide show antidote activity with respect to herbicide 2,4-D in sunflower seedlings. ^ EFFECT: improved method of synthesis. ^ 3 cl, 8 ex