INDOLE-2-CARBOXAMIDES AS INHIBITORS OF FACTOR Xa AND/OR VIIa, MEDICINAL AGENT BASED ON THEREOF AND METHOD FOR THEIR PREPARING

FIELD: organic chemistry, medicine, hematology, pharmacy. ^ SUBSTANCE: invention relates to novel compounds of the formula (I): in all their stereoisomeric forms and their mixtures taken in any ratio and their physiologically acceptable salts possessing properties of inhibitors of factor Xa and/or f...

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Bibliographische Detailangaben
Hauptverfasser:	UILL DEHVID UILL'JAM, RITTER KURT, MATTER KHANS, VENER FOL'KMAR, NAZARE MARK, EHSSRIKH MELANI
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, medicine, hematology, pharmacy. ^ SUBSTANCE: invention relates to novel compounds of the formula (I): in all their stereoisomeric forms and their mixtures taken in any ratio and their physiologically acceptable salts possessing properties of inhibitors of factor Xa and/or factor VIIa, and to a medicinal agent based on thereof. Also, invention relates to a method for synthesis of these compounds and their using for preparing pharmaceutical agents for inhibition of activity of factor Xa and/or factor VIIa or for their effect on blood coagulation or fibrinolysis. ^ EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. ^ 10 cl, 1 tbl, 276 ex