2-HETEROCYCLYL-1,2-ETHANEDIOL CARBAMATES

FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to 2-heterocyclyl-1,2-ethanediol carbamates of the formula (I) , their enantiomers, enantiomeric mixtures or pharmaceutically acceptable salts wherein A means a heterocyclic fragment chosen from the following group: ^ B1 an...

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Hauptverfasser:	CHOJ JONG-MOON, LI KI-KHO
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to 2-heterocyclyl-1,2-ethanediol carbamates of the formula (I) , their enantiomers, enantiomeric mixtures or pharmaceutically acceptable salts wherein A means a heterocyclic fragment chosen from the following group: ^ B1 and B2 mean independently hydroxy-group or -OCONR1R2 under condition that B1 and B2 don't mean hydroxy-group simultaneously; R1 and R2 mean hydrogen atom; R3, R4 and R5 mean alkyl, halogen atom, trihalogenmethyl, trialkylmethyl, -NO2, -CN and phenyl. These compounds can be used in treatment of the central nervous system disorders being especially as anticonvulsants and anti-epileptic agents. Also, invention describes a pharmaceutical composition based on compounds of the formula (I). ^ EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. ^ 12 cl, 1 tbl, 34 ex