METHOD FOR EVALUATING AUTOIMMUNITY TO HUMAN HEPATIC ANTIGEN

FIELD: medicine, laboratory diagnostics. ^ SUBSTANCE: the present innovation deals with evaluating autoimmunity to ganglioside of human hepatocytes. In blood serum due to immunoenzymatic assay one should detect the content of autoantibodies IgM and IgG to ganglioside of hepatic tissue, calculate the...

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Hauptverfasser: NEMOV VIKTOR VASIL'EVICH, IVASHKINA SVETLANA GEORGIEVNA
Format: Patent
Sprache:eng ; rus
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Beschreibung
Zusammenfassung:FIELD: medicine, laboratory diagnostics. ^ SUBSTANCE: the present innovation deals with evaluating autoimmunity to ganglioside of human hepatocytes. In blood serum due to immunoenzymatic assay one should detect the content of autoantibodies IgM and IgG to ganglioside of hepatic tissue, calculate the ratio of the content of autoantibodies in tested serum against their content in negative control, and at its value being above 1 it is possible to detect the presence of autoimmune process in human liver. The innovation enables to fulfill diagnostics of autoimmune process in hepatic tissue at higher accuracy and specificity. ^ EFFECT: increased accuracy and efficiency of evaluation.