MERCAPTOACETYLAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, METHOD FOR PRODUCTION THEREOF AND METHOD FOR TREATMENT OF CARDIOVASCULAR CONDITION
FIELD: pharmacology, medicine. ^ SUBSTANCE: invention relates to new mercaptoacetylamide derivatives, which represents angiotensine converting enzyme and neutral endopeptidase inhibitors and useful in treatment of cardiovascular condition. More particularly invention relates to derivatives of formul...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | ZOJRING BERNKHARD KLEEMANN KHAJNTS-VERNER KEL' DZHEK RODZHER FLINN GARI A JABLONKA BERND GERKEN MANFRED LINTS VOL'FGANG ANDERSON BARBARA EHNN MEKHDI SHUDZHAAT ZAJTS VERNER |
| description | FIELD: pharmacology, medicine. ^ SUBSTANCE: invention relates to new mercaptoacetylamide derivatives, which represents angiotensine converting enzyme and neutral endopeptidase inhibitors and useful in treatment of cardiovascular condition. More particularly invention relates to derivatives of formula I , wherein R1 represents hydrogen or acyl; wherein R2 represents hydrogen or biphenylmethyl; { represents -(CH2)n (n = 1, integer); B1 and B2 are independently hydrogen; or pharmaceutically acceptable salts or stereomers thereof. Method for production of compounds of formula I and formula II, pharmaceutical composition on the base of formula I, method for production thereof and method for treatment of cardiovascular condition. ^ EFFECT: new derivatives having value biological properties. ^ 14 cl, 3 tbl, 4 ex, 1 dwg |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2286346C2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2286346C2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2286346C23</originalsourceid><addsrcrecordid>eNqNjTFqw0AQRdWkCEnuMAdQGsmYtMPsKDug3RGjkcCVMGZdmcSg3CgXjWJSuEz1P7zH_4_Vd2IjHFyR2A89JgkMgU1mdJl5rGGIaGmjkwthD6Rp0FFcNG89O0qW_A4eGUZMXENijxqgU4PBNEx0UzdurB1gDveGG6Mnzg4bI7QgOuNIU4_2ux5uP8_Vw_l4WcvLXz5V0LFTfC3Xz6Ws1-OpfJSvxaamedu3uz017T-UHzHfRhc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>MERCAPTOACETYLAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, METHOD FOR PRODUCTION THEREOF AND METHOD FOR TREATMENT OF CARDIOVASCULAR CONDITION</title><source>esp@cenet</source><creator>ZOJRING BERNKHARD ; KLEEMANN KHAJNTS-VERNER ; KEL' DZHEK RODZHER ; FLINN GARI A ; JABLONKA BERND ; GERKEN MANFRED ; LINTS VOL'FGANG ; ANDERSON BARBARA EHNN ; MEKHDI SHUDZHAAT ; ZAJTS VERNER</creator><creatorcontrib>ZOJRING BERNKHARD ; KLEEMANN KHAJNTS-VERNER ; KEL' DZHEK RODZHER ; FLINN GARI A ; JABLONKA BERND ; GERKEN MANFRED ; LINTS VOL'FGANG ; ANDERSON BARBARA EHNN ; MEKHDI SHUDZHAAT ; ZAJTS VERNER</creatorcontrib><description>FIELD: pharmacology, medicine. ^ SUBSTANCE: invention relates to new mercaptoacetylamide derivatives, which represents angiotensine converting enzyme and neutral endopeptidase inhibitors and useful in treatment of cardiovascular condition. More particularly invention relates to derivatives of formula I , wherein R1 represents hydrogen or acyl; wherein R2 represents hydrogen or biphenylmethyl; { represents -(CH2)n (n = 1, integer); B1 and B2 are independently hydrogen; or pharmaceutically acceptable salts or stereomers thereof. Method for production of compounds of formula I and formula II, pharmaceutical composition on the base of formula I, method for production thereof and method for treatment of cardiovascular condition. ^ EFFECT: new derivatives having value biological properties. ^ 14 cl, 3 tbl, 4 ex, 1 dwg</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20061027&DB=EPODOC&CC=RU&NR=2286346C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20061027&DB=EPODOC&CC=RU&NR=2286346C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZOJRING BERNKHARD</creatorcontrib><creatorcontrib>KLEEMANN KHAJNTS-VERNER</creatorcontrib><creatorcontrib>KEL' DZHEK RODZHER</creatorcontrib><creatorcontrib>FLINN GARI A</creatorcontrib><creatorcontrib>JABLONKA BERND</creatorcontrib><creatorcontrib>GERKEN MANFRED</creatorcontrib><creatorcontrib>LINTS VOL'FGANG</creatorcontrib><creatorcontrib>ANDERSON BARBARA EHNN</creatorcontrib><creatorcontrib>MEKHDI SHUDZHAAT</creatorcontrib><creatorcontrib>ZAJTS VERNER</creatorcontrib><title>MERCAPTOACETYLAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, METHOD FOR PRODUCTION THEREOF AND METHOD FOR TREATMENT OF CARDIOVASCULAR CONDITION</title><description>FIELD: pharmacology, medicine. ^ SUBSTANCE: invention relates to new mercaptoacetylamide derivatives, which represents angiotensine converting enzyme and neutral endopeptidase inhibitors and useful in treatment of cardiovascular condition. More particularly invention relates to derivatives of formula I , wherein R1 represents hydrogen or acyl; wherein R2 represents hydrogen or biphenylmethyl; { represents -(CH2)n (n = 1, integer); B1 and B2 are independently hydrogen; or pharmaceutically acceptable salts or stereomers thereof. Method for production of compounds of formula I and formula II, pharmaceutical composition on the base of formula I, method for production thereof and method for treatment of cardiovascular condition. ^ EFFECT: new derivatives having value biological properties. ^ 14 cl, 3 tbl, 4 ex, 1 dwg</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjTFqw0AQRdWkCEnuMAdQGsmYtMPsKDug3RGjkcCVMGZdmcSg3CgXjWJSuEz1P7zH_4_Vd2IjHFyR2A89JgkMgU1mdJl5rGGIaGmjkwthD6Rp0FFcNG89O0qW_A4eGUZMXENijxqgU4PBNEx0UzdurB1gDveGG6Mnzg4bI7QgOuNIU4_2ux5uP8_Vw_l4WcvLXz5V0LFTfC3Xz6Ws1-OpfJSvxaamedu3uz017T-UHzHfRhc</recordid><startdate>20061027</startdate><enddate>20061027</enddate><creator>ZOJRING BERNKHARD</creator><creator>KLEEMANN KHAJNTS-VERNER</creator><creator>KEL' DZHEK RODZHER</creator><creator>FLINN GARI A</creator><creator>JABLONKA BERND</creator><creator>GERKEN MANFRED</creator><creator>LINTS VOL'FGANG</creator><creator>ANDERSON BARBARA EHNN</creator><creator>MEKHDI SHUDZHAAT</creator><creator>ZAJTS VERNER</creator><scope>EVB</scope></search><sort><creationdate>20061027</creationdate><title>MERCAPTOACETYLAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, METHOD FOR PRODUCTION THEREOF AND METHOD FOR TREATMENT OF CARDIOVASCULAR CONDITION</title><author>ZOJRING BERNKHARD ; KLEEMANN KHAJNTS-VERNER ; KEL' DZHEK RODZHER ; FLINN GARI A ; JABLONKA BERND ; GERKEN MANFRED ; LINTS VOL'FGANG ; ANDERSON BARBARA EHNN ; MEKHDI SHUDZHAAT ; ZAJTS VERNER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2286346C23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2006</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZOJRING BERNKHARD</creatorcontrib><creatorcontrib>KLEEMANN KHAJNTS-VERNER</creatorcontrib><creatorcontrib>KEL' DZHEK RODZHER</creatorcontrib><creatorcontrib>FLINN GARI A</creatorcontrib><creatorcontrib>JABLONKA BERND</creatorcontrib><creatorcontrib>GERKEN MANFRED</creatorcontrib><creatorcontrib>LINTS VOL'FGANG</creatorcontrib><creatorcontrib>ANDERSON BARBARA EHNN</creatorcontrib><creatorcontrib>MEKHDI SHUDZHAAT</creatorcontrib><creatorcontrib>ZAJTS VERNER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZOJRING BERNKHARD</au><au>KLEEMANN KHAJNTS-VERNER</au><au>KEL' DZHEK RODZHER</au><au>FLINN GARI A</au><au>JABLONKA BERND</au><au>GERKEN MANFRED</au><au>LINTS VOL'FGANG</au><au>ANDERSON BARBARA EHNN</au><au>MEKHDI SHUDZHAAT</au><au>ZAJTS VERNER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MERCAPTOACETYLAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, METHOD FOR PRODUCTION THEREOF AND METHOD FOR TREATMENT OF CARDIOVASCULAR CONDITION</title><date>2006-10-27</date><risdate>2006</risdate><abstract>FIELD: pharmacology, medicine. ^ SUBSTANCE: invention relates to new mercaptoacetylamide derivatives, which represents angiotensine converting enzyme and neutral endopeptidase inhibitors and useful in treatment of cardiovascular condition. More particularly invention relates to derivatives of formula I , wherein R1 represents hydrogen or acyl; wherein R2 represents hydrogen or biphenylmethyl; { represents -(CH2)n (n = 1, integer); B1 and B2 are independently hydrogen; or pharmaceutically acceptable salts or stereomers thereof. Method for production of compounds of formula I and formula II, pharmaceutical composition on the base of formula I, method for production thereof and method for treatment of cardiovascular condition. ^ EFFECT: new derivatives having value biological properties. ^ 14 cl, 3 tbl, 4 ex, 1 dwg</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2286346C2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MERCAPTOACETYLAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, METHOD FOR PRODUCTION THEREOF AND METHOD FOR TREATMENT OF CARDIOVASCULAR CONDITION |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T20%3A04%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ZOJRING%20BERNKHARD&rft.date=2006-10-27&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2286346C2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |