ASSOCIATED VACCINE AGAINST ANTHRAX AND PLAGUE IN CATTLE

FIELD: biotechnology. ^ SUBSTANCE: the suggested vaccine contains suspension of viable spores of anthracic vaccinal strain "55-VNIIBB&M" at initial concentration of 500-700 mln. spores/cu.cm, cultural virus-containing raw material of vaccinal virus of cattle plague of "LT" st...

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Hauptverfasser: GORSHKOVA TAT'JANA FEDOROVNA, GLUKHAREVA ELENA NIKOLAEVNA, ZHESTEREV VIKTOR IVANOVICH, KOSJACHENKO NATAL'JA SERGEEVNA, SELJANINOV JURIJ OLEGOVICH, EGOROVA IRINA JUR'EVNA, GREKHOVA NADEZHDA VASIL'EVNA
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: biotechnology. ^ SUBSTANCE: the suggested vaccine contains suspension of viable spores of anthracic vaccinal strain "55-VNIIBB&M" at initial concentration of 500-700 mln. spores/cu.cm, cultural virus-containing raw material of vaccinal virus of cattle plague of "LT" strain at activity of not less than 7.0 lg TCD50/cu. cm, lactosopeptonic stabilizing agent and distilled water at the following content of components,%: spores of anthracic strain "55-VNIIVV&M" -6.2 - 10.0; cultural raw material of cattle plague virus of "LT" strain -25.0 - 30.0; lactosopeptonic stabilizing agent -48.0 - 50.0; distilled water - the rest. One vaccinal dosage contains about 20-25 mln. anthracic spores and about 4.5-5.5 lg TCD50 of cattle plague virus The suggested vaccine is of high immunogenicity, develops tense immunity in once vaccinated cattle that lasts for 12 mo, not less, moreover, it is areactogenous, safe and stable at storage. ^ EFFECT: higher efficiency. ^ 3 ex, 3 tbl