ORALLY ADMINISTRATED LIQUID COMPOSITIONS COMPRISING GUAIFENESIN AND POLYOXYALKYLENE BLOCK-COPOLYMERS

FIELD: medicine, pharmacy. ^ SUBSTANCE: invention describes an orally administrated liquid composition used in treatment of respiratory diseases and comprising from 2% to 40% of guaifenesin and a filling agent comprising from 5% to 25% of polyoxyalkylene block-copolymer, from 30% to 90% of hydrophil...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	KHANOLKAR DZHAJANT EHKNAT, ROBBINS BRAJAN DZHEJMS, DOBROZHI DUGLAS DZHOZEF, DE LJA ARP SHEJN MAJKL, BILIN-KELLI FREHNSIS DZHOZEF DEHVID, MJULLE BENUA MORIS, KHEHJS DZHERRI UILL'JAM II
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	FIELD: medicine, pharmacy. ^ SUBSTANCE: invention describes an orally administrated liquid composition used in treatment of respiratory diseases and comprising from 2% to 40% of guaifenesin and a filling agent comprising from 5% to 25% of polyoxyalkylene block-copolymer, from 30% to 90% of hydrophilic solvent, and from 5% to 45% of water. The composition shows high physical stability in delivery of the concentrated doses of pharmaceutically active component, in particular, the active component doesn't show precipitation from solution for the prolonged times. Also, the composition remains in a liquid form in the mouth cavity that provides the effect of the pharmaceutically active agent of the composition on large areas in the mouth cavity mucosa. ^ EFFECT: enhanced effectiveness and valuable medicinal properties of agent. ^ 6 cl, 16 tbl, 1 dwg, 16 ex