SUBSTITUTED 2-ANILINOBENZIMIDAZOLES, THEIR USING AS INHIBITORS OF NA+/H+-EXCHANGE AND MEDICINAL AGENT COMPRISING THEREOF

FIELD: organic chemistry, medicine. ^ SUBSTANCE: invention describes a compound of the formula (I): representing such compound as 2-(2,6-dichlorophenylamino)-1H-benzimidazol-4-ol and others. Also, invention relates to using these compounds for preparing a medicinal agent used in treatment of disease...

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Bibliographische Detailangaben
Hauptverfasser:	KHOFMAJSTER ARMIN, BLJAJKH MARKUS, VIRT KLAUS, LANG KHANS-JOKHEN, GEKLE MIKHEL, KHAJNEL'T UVE
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, medicine. ^ SUBSTANCE: invention describes a compound of the formula (I): representing such compound as 2-(2,6-dichlorophenylamino)-1H-benzimidazol-4-ol and others. Also, invention relates to using these compounds for preparing a medicinal agent used in treatment of diseases associated with inhibition of [Na+/H+]-exchange. Proposed compounds can be used, in particular, in treatment and prophylaxis of impairment of respiratory impulse, acute and chronic renal diseases. ^ EFFECT: valuable medicinal properties of compounds. ^ 17 cl, 19 ex