METHOD FOR TREATING ONCOLOGICAL PATIENTS WITH VAGINAL TUMOR LESION

FIELD: medicine, oncology. ^ SUBSTANCE: one should carry out chemoradiation therapy at applying a cytostatic preparation followed by distance and intracavitary irradiation. Depending upon development of tumor lesion during the first 3 or 6 d it is necessary to conduct monochemotherapy only due to in...

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Hauptverfasser: OLTARZHEVSKAJA NATALIJA DMITRIEVNA, TITOVA VERA ALEKSEEVNA, KHARCHENKO NATALIJA VLADIMIROVNA, KOROVINA MARIJA ANATOL'EVNA, KREJNINA JULIJA MIKHAJLOVNA
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine, oncology. ^ SUBSTANCE: one should carry out chemoradiation therapy at applying a cytostatic preparation followed by distance and intracavitary irradiation. Depending upon development of tumor lesion during the first 3 or 6 d it is necessary to conduct monochemotherapy only due to introducing proxiphen together with dimethyl sulfoxide at weight ratio of 4.5-5.0 : 0.5-1.5, correspondingly by applications in "Coletex" napkins. Moreover, a napkin should be pre-impregnated in 20%-dimethylsulfoxide solution and fixed with a tough vaginal tamponade by changing napkins every 24 h. Then since the 4th d or the 7th d simultaneously with application it is necessary to carry out contact irradiation and distance impact onto minor pelvis every 4-6 h at single focal dosage (SFD) being 2 Gy at 10 seances 5 times/weekly with high-activity sources of SFD 2 Gy. The innovation provides tumor regress under conditions of no therapeutic complications, thus, improving patients' quality of life. ^ EFFECT: higher therapy. ^ 3 ex