PERCIQUINNINE, METHOD FOR ITS PREPARING AND ITS USING AS PHARMACEUTICAL AGENT

FIELD: organic chemistry, biochemistry, biotechnology, pharmacy. ^ SUBSTANCE: invention relates to a compound named perciquinnine of the molecular formula C12H16O3 that can be prepared by culturing fungus ST 001837 (DSM 13303) belonging to basidiomycetes Stereum complicatum and to its pharmaceutical...

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Hauptverfasser:	KURTS MIKHEL, MJULLER GJUNTER, TOTI LUIDZHI, KHOPMANN KORDULA
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, biochemistry, biotechnology, pharmacy. ^ SUBSTANCE: invention relates to a compound named perciquinnine of the molecular formula C12H16O3 that can be prepared by culturing fungus ST 001837 (DSM 13303) belonging to basidiomycetes Stereum complicatum and to its pharmaceutically acceptable salts used as inhibitors of lipase. Perciquinnine is prepared by a method involving culturing basidiomycetes of species ST 001837 (DSM 13303) belonging to class of basidiomycetes Stereum complicatum under aerobic conditions in nutrient medium containing carbon and nitrogen sources followed by its isolation and purification. Invention provides the development of pharmaceutical composition possessing ability to inhibit activity of lipase. ^ EFFECT: improved preparing method, valuable biochemical property of agent. ^ 7 cl, 2 tbl, 6 ex