2'-AMINO-2'-DEOXYNUCLEOSIDES AS INHIBITORS IF MEASLES AND MARBURG VIRUSUS REPRODUCTION
FIELD: organic chemistry, biochemistry, medicine, virology. ^ SUBSTANCE: invention relates to derivatives of 2'=amino-2'-deoxynucleosides of the formula: ^ wherein R means hydrogen atom (H), alkyl, aminoalkyl; R1 means -(R2NR3) wherein R2 and/or R3 means H, -OH, -NH2, alkyl, benzyl under c...
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| creator | ALEKSANDROVA L.A POKROVSKIJ A.G KUKHANOVA M.K IL'ICHEVA T.N BELANOV E.F VOLKOV G.N |
| description | FIELD: organic chemistry, biochemistry, medicine, virology. ^ SUBSTANCE: invention relates to derivatives of 2'=amino-2'-deoxynucleosides of the formula: ^ wherein R means hydrogen atom (H), alkyl, aminoalkyl; R1 means -(R2NR3) wherein R2 and/or R3 means H, -OH, -NH2, alkyl, benzyl under condition that R doesn't represent H or methyl when R2 and R3 mean H. Compounds elicit an antiviral activity with respect to measles and Marburg viruses exceeding that of ribavirin. ^ EFFECT: valuable properties of compounds. ^ 4 tbl, 2 dwg, 18 ex |
| format | Patent |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | 2'-AMINO-2'-DEOXYNUCLEOSIDES AS INHIBITORS IF MEASLES AND MARBURG VIRUSUS REPRODUCTION |
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