BENZAMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION ELICITING ENHANCED SOLUBILITY AND ABSORPTION CAPACITY IN ORAL APPLYING

FIELD: chemical-pharmaceutical industry, pharmacy. ^ SUBSTANCE: invention relates to a new pharmaceutical composition comprising benzamide derivative and one or some additives taken among the following substances: 1) mixture of polyethylene glycol and surface-active substance; 2) amino acid or inorg...

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Bibliographische Detailangaben
Hauptverfasser:	SUZUKI TSUNEDZI, ANDO TOMOJUKI, SAKAI IKUO, ISIBASI MASAKHIKO, SAKABE MASAKHIRO
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: chemical-pharmaceutical industry, pharmacy. ^ SUBSTANCE: invention relates to a new pharmaceutical composition comprising benzamide derivative and one or some additives taken among the following substances: 1) mixture of polyethylene glycol and surface-active substance; 2) amino acid or inorganic acid salt, and 3) propylene carbonate. The composition comprises benzamide derivative taken in the amount from 0.001 to 1000 mg per a single dosing formulation. The composition shows the enhanced solubility and absorption capacity in oral route of administration. ^ EFFECT: improved medicinal and pharmaceutical properties of composition. ^ 9 cl, 4 tbl, 1 dwg, 5 ex