LIQUID PREPARATION CONTAINING IMMUNOGLOBULIN EFFICIENT AGAINST MARBURG FEVER FROM HORSE BLOOD SERUM (HORSE IMMUNOGLOBULIN MARBURG)

FIELD: clinical immunology. ^ SUBSTANCE: preparation represents 9.0-11.0% solution of horse blood serum immunoglobulins with pH 7.0-7.5 and content of gamma-immunoglobulin fraction at least 90.0% of the total protein. Nonspecific fractions in preparation are albumin, alpha- and beta-globulin fractio...

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Hauptverfasser: POTRYVAEVA N.V, MIKHAJLOV V.V, BORISEVICH I.V, KRASNJANSKIJ V.P, MEL'NIKOV S.A, TIMAN'KOVA G.D
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: clinical immunology. ^ SUBSTANCE: preparation represents 9.0-11.0% solution of horse blood serum immunoglobulins with pH 7.0-7.5 and content of gamma-immunoglobulin fraction at least 90.0% of the total protein. Nonspecific fractions in preparation are albumin, alpha- and beta-globulin fractions in amount not larger than 10.0%, and residual ethyl alcohol in amount not larger than 4.0%. Preparation is characterized by virus-neutralizing antibodies against virus Marburg. Titer of virus-neutralizing antibodies is at least 1:2048 and can be used for emergency prevention of Marburg fever in humans. ^ EFFECT: extended immunoglobulin application area. ^ 1 tbl