METHOD FOR PREPARING BIS-(1-VINYLIMIDAZOLE)ZINC DIACETATE

FIELD: chemistry of organometallic compounds, chemical technology. ^ SUBSTANCE: invention relates to the improved method for preparing the chelate compound bis-(1-vinylimidazole)zinc diacetate (I) representing the medicinal preparation of acizol that is the effective antidote and antioxidant. Method...

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Bibliographische Detailangaben
Hauptverfasser:	NECHIPORENKO S.P, KHAMIDULLIN N.M, BABANIJAZOV KH.KH, TROFIMOV B.A, PRONINA N.V, BAJKALOVA L.V, STANKEVICH V.K, NEKRASOV M.S
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	FIELD: chemistry of organometallic compounds, chemical technology. ^ SUBSTANCE: invention relates to the improved method for preparing the chelate compound bis-(1-vinylimidazole)zinc diacetate (I) representing the medicinal preparation of acizol that is the effective antidote and antioxidant. Method for preparing the compound (I) is carried out in the absence of organic solvents at temperature 20-35°C in the mole ratio 1-vinylimidazole : zinc diacetate in the range from 10:1 to 3:1. Method provides exclusion fire hazard and explosion hazard solvent from the technological process and enhancement of the yield of highly pure acizol satisfied for Pharmacopoeia requirements. ^ EFFECT: improved method for preparing. ^ 2 cl, 4 ex