METHOD FOR PRODUCTION OF MELIOIDOSIC IMMUNE SERUM

FIELD: microbiology and immunology, in particular immunodiagnosis. ^ SUBSTANCE: atypical strain of melioidose Burkholderia pseudomallei-111-6-1 with altered phenotype defected with respect to synthesis of 8 antigen and acting as immunosuppressor is used as antigen for animal immunization. Immune ser...

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Hauptverfasser:	PUSHKAR' V.G, PIVEN' N.N, KAPLIEV V.I, ALEKSEEV V.V, KULAKOV M.JA, PLEKHANOVA N.G, VOBLENKO R.A
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	FIELD: microbiology and immunology, in particular immunodiagnosis. ^ SUBSTANCE: atypical strain of melioidose Burkholderia pseudomallei-111-6-1 with altered phenotype defected with respect to synthesis of 8 antigen and acting as immunosuppressor is used as antigen for animal immunization. Immune serum is obtained after 2 immunization cycles of animal-producer with titer in gel immunodiffusion reaction not less than 1:128. ^ EFFECT: immune serum with increased specific activity. ^ 2 tbl, 2 ex