METHOD FOR PREVENTING CARDIO-VASCULAR DISEASES IN WOMEN AT CLIMACTERIC PERIOD AT THE BACKGROUND OF SUBSTITUTE HORMONAL THERAPY

FIELD: medicine. ^ SUBSTANCE: before applying substitute hormonal therapy (SHT) on should evaluate antithrombogenic activity of vascular wall in women. For this purpose one should determine quantitative values of ADP-induced aggregation of thrombocytes, activity of antithrombin III in blood and fibr...

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Hauptverfasser:	BUBNOVA G.V, BULGAKOV R.V, KRAVTSOV N.G, LOBANOVA E.G, ZAJTSEVA T.A, FIRSOVA T.A, JAKUSHEVA E.G, ISHCHENKO A.I, STEPANKOVA I.M, LANCHINSKIJ V.I, POPKOVA A.M, GAL'TSOVA N.E, MALINOV O.A, POPKOV S.A, SHPACHENKO V.V, KOVALEV M.I
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	DIAGNOSIS HUMAN NECESSITIES HYGIENE IDENTIFICATION MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SURGERY
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Zusammenfassung:	FIELD: medicine. ^ SUBSTANCE: before applying substitute hormonal therapy (SHT) on should evaluate antithrombogenic activity of vascular wall in women. For this purpose one should determine quantitative values of ADP-induced aggregation of thrombocytes, activity of antithrombin III in blood and fibrinolytic blood activity both before and after "cuff"-test. Then one should detect the indices calculated as the ratio of mentioned values both before and after carrying out the mentioned test. If mentioned indices are decreased against the norm by 20-40% women should be prescribed to undergo SHT at additional introduction of aspirin and supradin. The method provides prophylaxis of cardio-vascular diseases in this category of female patients due to correcting affected functional activity of vascular endothelium. ^ EFFECT: higher efficiency of prophylaxis. ^ 1 cl, 1 ex, 4 tbl