ENDOGENIC PHARMACEUTICAL COMPOSITION PREPARED ON BASIS OF GOAL-SEEKING ACTIVATION OF HUMORAL MEDIATORS OF BRAIN CORTEX NERVE ENDING

FIELD: medicine, biotechnology, pharmacy. ^ SUBSTANCE: invention relates to agents used for treatment of pathological states associated with disorder of synthesis of neuromediating substances. Method involves the development of pharmaceutical composition and a method for it preparing. Pharmaceutical...

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Hauptverfasser: LATSERUS F.EH, PINIGINA N.M, LATSERUS L.A
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine, biotechnology, pharmacy. ^ SUBSTANCE: invention relates to agents used for treatment of pathological states associated with disorder of synthesis of neuromediating substances. Method involves the development of pharmaceutical composition and a method for it preparing. Pharmaceutical composition represents subcellular synaptosomal fractions: synaptic membranes, "light" synaptosomes and "heavy" synaptosomes prepared from gray matter of cerebral hemispheres from experimental animals based on the goal-seeking modification of humoral mediators of nerve endings transformed to synaptosomes in development and regression of malignant processes. The composition provides inhibiting the growth of tumor cells, to elevate span-life of patients with ascite Ehrlich's sarcoma, breast adenocarcinoma Ca-755, Wolker's carcinosarcoma-256. ^ EFFECT: valuable medicinal and anti-tumor properties of composition. ^ 12 cl, 3 tbl, 3 ex