COLD-SAFETY SOLUTION FOR FREEZING LEUKOCYTES AT SUB-MODERATE TEMPERATURE

FIELD: medicine, physiology. ^ SUBSTANCE: invention relates to creating cold-safety solution for freezing leukocytes and their retaining in physiologically active state after thawing. Cold-safety solution for freezing leukocytes in the ratio 1:1 at moderately low temperature and pH 7.0-7.4 contains...

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Bibliographische Detailangaben
Hauptverfasser:	UTEMOV S.V, SHCHEGLOVA O.O, DEVET'JAROVA O.N, TUMANOVA T.V, SVEDENTSOV E.P, KOSTJAEV A.A
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	FIELD: medicine, physiology. ^ SUBSTANCE: invention relates to creating cold-safety solution for freezing leukocytes and their retaining in physiologically active state after thawing. Cold-safety solution for freezing leukocytes in the ratio 1:1 at moderately low temperature and pH 7.0-7.4 contains hexamethylene-bis-tetraoxyethylurea and water for injection. Leukocytes are frozen to -20oC being solution contains additionally hydroxymethylethylpyridine succinate in the following ratio of components, %: hexamethylene-bis-tetraoxyethylurea, 26.0-30.0; hydroxymethylethylpyridine succinate, 0.1-0.2, and water for injection, up to 100 ml. Cold-safety solution in freezing leukocytes concentrate to -20oC provides the safety of high percent of physiologically active leukocyte cells. ^ EFFECT: valuable properties of solution. ^ 3 tbl, 1 ex