METHOD FOR DIAGNOSING INDIVIDUAL BRAIN SENSITIVITY TO ISCHEMIA

FIELD: medicine. ^ SUBSTANCE: method involves determining availability of p53 gene in /+(O/R) genotype from allelic polymorphism in Bam HI RELP restrictase recognition site in 5 exon of this gene. The gene being found, large-scale ischemic brain lesion (greater than 90 cm3) is predicted with probabi...

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Hauptverfasser: SHETOVA I.M, LIMBORSKAJA S.A, SLOMINSKIJ P.A, TUPITSYNA T.V, SKVORTSOVA V.I, KOL'TSOVA E.A
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine. ^ SUBSTANCE: method involves determining availability of p53 gene in /+(O/R) genotype from allelic polymorphism in Bam HI RELP restrictase recognition site in 5 exon of this gene. The gene being found, large-scale ischemic brain lesion (greater than 90 cm3) is predicted with probability greater than 75% in the cases of blood supply disorder under minimum probability of small-scale (below 40 cm3) infarctions. ^ EFFECT: high accuracy in determining persons of high sensitivity among practically health people. ^ 1 tbl