PRELIMINARY PREPARED EMULSION CONCENTRATES CONTAINING CYCLOSPORINE OR MACROLIDE

FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to a composition in the form of preliminary prepared emulsion or microemulsion concentrate designated for oral administration and comprising cyclosporine or macrolide and a carrier and also to soft or solid gelatin capsule containing the indi...

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Hauptverfasser: AMBJUL' MIKHAEHL', LJUKKEL' BARBARA, RIKHTER FRIDRIKH, KHEHBERLIN BARBARA, MAJNTSER ARMIN
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creator AMBJUL' MIKHAEHL'
LJUKKEL' BARBARA
RIKHTER FRIDRIKH
KHEHBERLIN BARBARA
MAJNTSER ARMIN
description FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to a composition in the form of preliminary prepared emulsion or microemulsion concentrate designated for oral administration and comprising cyclosporine or macrolide and a carrier and also to soft or solid gelatin capsule containing the indicated composition and to a method for reducing variability of bioavailability levels of cyclosporine or macrolide using the indicated composition. Composition elicits improved indices of bioavailability and reduced variability of bioavailability parameters. ^ EFFECT: improved and valuable properties of composition. ^ 18 cl, 1 tbl, 1 ex
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PRELIMINARY PREPARED EMULSION CONCENTRATES CONTAINING CYCLOSPORINE OR MACROLIDE
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