PRELIMINARY PREPARED EMULSION CONCENTRATES CONTAINING CYCLOSPORINE OR MACROLIDE

FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to a composition in the form of preliminary prepared emulsion or microemulsion concentrate designated for oral administration and comprising cyclosporine or macrolide and a carrier and also to soft or solid gelatin capsule containing the indi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	AMBJUL' MIKHAEHL', LJUKKEL' BARBARA, RIKHTER FRIDRIKH, KHEHBERLIN BARBARA, MAJNTSER ARMIN
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to a composition in the form of preliminary prepared emulsion or microemulsion concentrate designated for oral administration and comprising cyclosporine or macrolide and a carrier and also to soft or solid gelatin capsule containing the indicated composition and to a method for reducing variability of bioavailability levels of cyclosporine or macrolide using the indicated composition. Composition elicits improved indices of bioavailability and reduced variability of bioavailability parameters. ^ EFFECT: improved and valuable properties of composition. ^ 18 cl, 1 tbl, 1 ex