METHOD FOR PREDICTING PREGNANCY FLOW AND DETECTING RISK DEGREE IN FAILED DEVELOPMENT OF FETUS/EMBRYO AND CHILD'S BIRTH AT DIFFERENT DEFECTS

FIELD: medicine, diagnostics, obstetrics. ^ SUBSTANCE: one should apply a test system for IEA containing plots with sorbed fractions of nonhistonic anionic proteins of cerebral tissue chromatin (FACBP-C) and/or membranous cerebral proteins (FMP-C). One should detect immunoreactivity of serumal autoa...

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Hauptverfasser: SOBOLEV V.A, SIDJAKIN A.A, MOROZOV S.G, GRIBOVA I.E, SHCHEKAEVA E.I, USANOVA M.P, GNEDENKO B.B, PROTSENKO A.N
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine, diagnostics, obstetrics. ^ SUBSTANCE: one should apply a test system for IEA containing plots with sorbed fractions of nonhistonic anionic proteins of cerebral tissue chromatin (FACBP-C) and/or membranous cerebral proteins (FMP-C). One should detect immunoreactivity of serumal autoantibodies to FACBP-C and FMP-C. If reaction intensity (RI) of tested serum (TS) is not beyond the limits: -15 : +40% against reaction of serum taken as a standard one should conclude that TS belongs to group K1 - norm; if RI is beyond the limits of K1 but is not less than -25% and not higher than 65% - it should be referred to group K2 - weak deviations; if it is beyond limits of K1 and K2 but is not below -45% and not higher than 100% - to the third group K3 - moderate deviations; if it lies beyond the limits of K1, K2 and K3 but it id not less than -65% and not higher than 150% - to group K4 - considerable deviations; if it is beyond K4 limits, by negative values it is below -65% and by positive values ranges within 150% up to 200% - it should be referred to K5 group - acute deviations, and if it is beyond the limits of K1, K2, K3, K4 and K5 - it should be referred to group K6 -very sharp, exquisite deviations and it is possible to predict the risk for failed development of fetus/embryo at increasing the group from K1 to K6. ^ EFFECT: higher reliability of the present predictions. ^ 2 cl, 9 ex, 2 tbl