METHOD FOR PREPARING SEROTONIN AND ITS PHARMACOLOGICAL SALTS

METHOD FOR PREPARING SEROTONIN AND ITS PHARMACOLOGICAL SALTS

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing serotonin and its water-soluble pharmacologically acceptable salts. Method involves reduction of 5-benzyloxytryptamine or 5-benzyloxy-3-(2-nitroethyl)-indole in hydrogen flow in the presence of 10% pa...

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Bibliographische Detailangaben
Hauptverfasser: PANOV A.E, MIKERIN I.E, KRJUKOV L.N, KUZNETSOV S.L, ALFEROV A.V, VORONTSOV E.A, SEVERIN E.S
Format: Patent
Sprache:eng ; rus
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing serotonin and its water-soluble pharmacologically acceptable salts. Method involves reduction of 5-benzyloxytryptamine or 5-benzyloxy-3-(2-nitroethyl)-indole in hydrogen flow in the presence of 10% palladium on activated carbon as a catalyst. Process is carried out under pressure 20-30 atm. Method provides preparing end products with the yield 90-97%. EFFECT: improved preparing method, high yield. 3 cl, 5 sch, 4 ex