ADENOVIRUS-RECOMBINANT CARRYING ADENOVIRAL VECTOR STRUCTURE (VARIANTS), METHOD FOR RECOVERY FUNCTION OF PROTEIN P53 IN TUMOR CELL WITH DEFICIENCY OF NATURAL P53, METHOD FOR PRODUCING ADENOVIRUS-RECOMBINANT

FIELD: genetic engineering, virology, medicine, oncology. SUBSTANCE: invention proposes adenovirus-recombinant comprising adenoviral vector that contains the natural gene p53 expressing protein p53 in mammalian cells. Effect of enhancement of protein p53 level in body is used in method for recovery...

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Hauptverfasser: SHANG UEHJ-UEHJ, ROT DZHEK A
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: genetic engineering, virology, medicine, oncology. SUBSTANCE: invention proposes adenovirus-recombinant comprising adenoviral vector that contains the natural gene p53 expressing protein p53 in mammalian cells. Effect of enhancement of protein p53 level in body is used in method for recovery function of protein p53 in tumor cell. Invention provides prophylaxis of tumor cells growth. EFFECT: valuable medicinal properties of adenovirus-recombinant. 34 cl, 24 dwg, 2 tbl, 7 ex