METHOD OF GRINDING FOR PREPARING FINELY DIVIDED MEDICAL SUBSTANCES

FIELD: drug formulation. SUBSTANCE: medicament is subjected to spray-type grinding using as milling media air or nitrogen having moisture content within a range of 30 to 90%. Resulting substance has particle size below 10 mcm and 5% amorphous phase. EFFECT: enabled preparation of inhalation-suitable...

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Bibliographische Detailangaben
Hauptverfasser:	BRAUN EHNDRJU B, VEMURI N. MURTI, KHOSEK PATRIK, OTELEN ZHAN-RENE
Format:	Patent
Sprache:	eng
Schlagworte:	CRUSHING, PULVERISING, OR DISINTEGRATING CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE MILLING GRAIN PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PREPARATORY TREATMENT OF GRAIN FOR MILLING SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRANSPORTING
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Beschreibung
Zusammenfassung:	FIELD: drug formulation. SUBSTANCE: medicament is subjected to spray-type grinding using as milling media air or nitrogen having moisture content within a range of 30 to 90%. Resulting substance has particle size below 10 mcm and 5% amorphous phase. EFFECT: enabled preparation of inhalation-suitable form. 10 cl, 1 tbl