NEW POLYPEPTIDE COMPOUND

FIELD: organic chemistry, polypeptides, pharmacy. SUBSTANCE: invention relates to new poly- peptide compounds of the general formula [I]: wherein R1 means hydrogen atom arylamino-(lower)-alkanoyl that can comprise one or some suitable substituents, aroyl substituted with heterocyclic group that can comprise one or some suitable substituents; aroyl substituted with aryl comprising higher alkyl; aroyl substituted with aryl comprising lower alkyl; aryl-C2-C6-alkanoyl substituted with aryl comprising lower alkyl; lower alkanoyl substituted with unsaturated condensed heterocyclic group that can comprise one or some suitable substituents; lower alkanoyl substituted with pyridyl that can comprise one or some suitable substituents; amino-protecting group, hexylnaphthtoyl; aroyl substituted with heterocyclylcarbamoyl that can comprise one or some suitable substituents; lower alkanoyl substituted with cyclo-(lower)-alkyl that can comprise one or some suitable substituents; lower alkanoyl substituted with thienyl comprising heterocyclic group that can comprise one or some suitable substituents; or lower alkenoyl substituted with heterocyclic group that can comprise one or some suitable substituents; R2 means hydrogen atom of hydroxy-group; R3 means hydroxy-, hydroxysulfonyloxy- or lower alkoxy-group; R4 means hydroxy- or lower alkoxy-group; or to their salts eliciting antifungal activity. Invention relates to two methods for preparing compounds of the general formula (I), pharmaceutical composition eliciting antifungal activity and method for prophylactic and/or therapeutic treatment of infectious diseases caused by fungi. EFFECT: valuable medicinal properties of compound. 10 cl, 4 tbl, 338 ex