DERIVATIVES OF 2-AMINOPYRIDINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS PREPARING
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to new derivatives of 2-aminopyridines of the formula (I) wherein C means unsubstituted or substituted phenyl, pyridyl, thienyl, thiazolyl, quinolyl, quinoxaline-2-yl or their benzoanellated derivatives; D means unsubstituted or substi...
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| creator | KIRSH RAJNKHARD FRIK VENDELIN GLOMBIK KHAJNER KHOJER KHUBERT |
| description | FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to new derivatives of 2-aminopyridines of the formula (I) wherein C means unsubstituted or substituted phenyl, pyridyl, thienyl, thiazolyl, quinolyl, quinoxaline-2-yl or their benzoanellated derivatives; D means unsubstituted or substituted phenyl, pyridyl, thienyl, pyrimidyl, indolyl, thiazolyl, imidazolyl, quinolyl, triazolyl, oxazolyl, isoxazolyl or their benzoanellated derivatives under condition that C and D have no the following values simultaneously: C phenyl and D phenyl, C phenyl and D pyridyl, C pyridyl and D phenyl, C pyridyl and D pyridyl; R1-R4 mean hydrogen atom, NO2 or NH2. Compounds of the formula (I) elicit hypolipidemic activity and can be used in medicine for treatment of lipid metabolism disorders. EFFECT: improved preparing method, valuable medicinal properties of compounds. 4 cl, 1 tbl, 66 ex |
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SUBSTANCE: invention relates to new derivatives of 2-aminopyridines of the formula (I) wherein C means unsubstituted or substituted phenyl, pyridyl, thienyl, thiazolyl, quinolyl, quinoxaline-2-yl or their benzoanellated derivatives; D means unsubstituted or substituted phenyl, pyridyl, thienyl, pyrimidyl, indolyl, thiazolyl, imidazolyl, quinolyl, triazolyl, oxazolyl, isoxazolyl or their benzoanellated derivatives under condition that C and D have no the following values simultaneously: C phenyl and D phenyl, C phenyl and D pyridyl, C pyridyl and D phenyl, C pyridyl and D pyridyl; R1-R4 mean hydrogen atom, NO2 or NH2. Compounds of the formula (I) elicit hypolipidemic activity and can be used in medicine for treatment of lipid metabolism disorders. 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SUBSTANCE: invention relates to new derivatives of 2-aminopyridines of the formula (I) wherein C means unsubstituted or substituted phenyl, pyridyl, thienyl, thiazolyl, quinolyl, quinoxaline-2-yl or their benzoanellated derivatives; D means unsubstituted or substituted phenyl, pyridyl, thienyl, pyrimidyl, indolyl, thiazolyl, imidazolyl, quinolyl, triazolyl, oxazolyl, isoxazolyl or their benzoanellated derivatives under condition that C and D have no the following values simultaneously: C phenyl and D phenyl, C phenyl and D pyridyl, C pyridyl and D phenyl, C pyridyl and D pyridyl; R1-R4 mean hydrogen atom, NO2 or NH2. Compounds of the formula (I) elicit hypolipidemic activity and can be used in medicine for treatment of lipid metabolism disorders. EFFECT: improved preparing method, valuable medicinal properties of compounds. 4 cl, 1 tbl, 66 ex</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DERIVATIVES OF 2-AMINOPYRIDINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS PREPARING |
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