DERIVATIVES OF 2-AMINOPYRIDINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS PREPARING

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to new derivatives of 2-aminopyridines of the formula (I) wherein C means unsubstituted or substituted phenyl, pyridyl, thienyl, thiazolyl, quinolyl, quinoxaline-2-yl or their benzoanellated derivatives; D means unsubstituted or substi...

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Hauptverfasser:	KIRSH RAJNKHARD, FRIK VENDELIN, GLOMBIK KHAJNER, KHOJER KHUBERT
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to new derivatives of 2-aminopyridines of the formula (I) wherein C means unsubstituted or substituted phenyl, pyridyl, thienyl, thiazolyl, quinolyl, quinoxaline-2-yl or their benzoanellated derivatives; D means unsubstituted or substituted phenyl, pyridyl, thienyl, pyrimidyl, indolyl, thiazolyl, imidazolyl, quinolyl, triazolyl, oxazolyl, isoxazolyl or their benzoanellated derivatives under condition that C and D have no the following values simultaneously: C phenyl and D phenyl, C phenyl and D pyridyl, C pyridyl and D phenyl, C pyridyl and D pyridyl; R1-R4 mean hydrogen atom, NO2 or NH2. Compounds of the formula (I) elicit hypolipidemic activity and can be used in medicine for treatment of lipid metabolism disorders. EFFECT: improved preparing method, valuable medicinal properties of compounds. 4 cl, 1 tbl, 66 ex