1-(3-HETEROARYLPROPYL OR PROP-2-ENYL)-4-BENZYLPIPERIDINES, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF

FIELD: organic chemistry, medicine, neurology, pharmacy. SUBSTANCE: invention relates to 1-(3- heteroarylpropyl or prop-2-enyl)-4-benzylpiperidines of the formula (I) wherein X means oxygen atom, NR1, sulfur atom or CH2; Y means CH; Z means CH; Y and X in common can mean C=C; R1, R2, R3 mean hydroge...

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Bibliographische Detailangaben
Hauptverfasser:	BARBER EHNDRJU, PRJUKHER KHEL'MUT, LAJBROK JOAKHIM, BARTOSHIK GERD
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: organic chemistry, medicine, neurology, pharmacy. SUBSTANCE: invention relates to 1-(3- heteroarylpropyl or prop-2-enyl)-4-benzylpiperidines of the formula (I) wherein X means oxygen atom, NR1, sulfur atom or CH2; Y means CH; Z means CH; Y and X in common can mean C=C; R1, R2, R3 mean hydrogen atom; R4 means fluorine atom. Invention describes also method for preparing these compounds, pharmaceutical composition for treatment and prophylaxis of cerebral disorders based on these compounds and method for preparing pharmaceutical composition. Invention provides preparing new compounds eliciting valuable biological properties. Invention can be used in medicine as medicinal agent for treatment and prophylaxis of cerebral disorders. EFFECT: improved preparing method, valuable medicinal properties of compounds. 6 cl, 1 tbl, 3 ex