INACTIVATED EMULSION VACCINE AGAINST HEN'S HYDROPERICARDITIS SYNDROME (HHPS)

FIELD: veterinary virology, biotechnology. SUBSTANCE: the suggested vaccine contains antigenic material as 5-10%-virus-containing suspension out of KR95N114 HHPS virus, inactivating agent as ethylenimine dimer and oily adjuvant in efficient ratio. Strain is deposited in VGNKI collection of microorga...

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Bibliographische Detailangaben
Hauptverfasser:	BORISOVA O.A, GUSEV A.A, SMOLENSKIJ V.I, PARFENOVA I.L, BORISOV A.V, SURNEV D.S, BORISOV V.V
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	FIELD: veterinary virology, biotechnology. SUBSTANCE: the suggested vaccine contains antigenic material as 5-10%-virus-containing suspension out of KR95N114 HHPS virus, inactivating agent as ethylenimine dimer and oily adjuvant in efficient ratio. Strain is deposited in VGNKI collection of microorganisms , registration code being KR95N114 DEP. Strain KR95N114 is reproduced in liver of 5-50-d-aged chickens or in primary hepatic cell culture of SPF-hens' embryos at biological activity of 3,25/5,0 lg LD50/0,2cu.cm. Vaccine suggested is nonreactogenic, harmless for vaccinated poultry. Moreover, titer of antibodies corresponds to 4,61-4,85 log2. EFFECT: higher efficiency. 8 cl, 11 ex, 9 tbl