METHOD FOR EVALUATING HUMORAL ORGAN-SPECIFIC IMMUNITY LEVEL IN THE CASES OF AUTOIMMUNE DISEASES AND STATES

FIELD: medicine. SUBSTANCE: method involves covering solid body carrier having organ-specific antigens absorbed thereon with control serum and sera under study in working dilution of 1:100. Immunoenzyme analysis is carried out and optical density of the control serum and sera under study is measured...

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Hauptverfasser: PODDUBIKOV A.V, VANEEVA N.P, JASTREBOVA N.E, TSVETKOVA N.V, MARKINA O.A
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine. SUBSTANCE: method involves covering solid body carrier having organ-specific antigens absorbed thereon with control serum and sera under study in working dilution of 1:100. Immunoenzyme analysis is carried out and optical density of the control serum and sera under study is measured to determine by difference between optical density of sample under study and negative control sample interpreted in terms of availability of antibodies to various organ-specific antigens. The value being equal to or greater than 0.2, active humoral immunity with respect to particular organ is considered to take place. EFFECT: high accuracy in determining immunity activity with respect to particular organ and in determining process propagation over a system of organs. 4 tbl