VACCINE AGAINST INFECTIONS INDUCED BY OPPORTUNISTIC PATHOGENS

FIELD: medicine, infectious diseases. SUBSTANCE: vaccine represents the combination of antigens of opportunistic microorganisms with high-molecular synthetic carrier as N-hydroxy-1,4-ethylene piperazine and N-(carboxyethyl)-1,4-ethylene piperazinium bromide of molecular mass 30 000-120 000 Da with r...

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Hauptverfasser:	PUCHKOVA N.G, MIKHAJLOVA N.A, KHAITOV R.M, KUNJAGINA O.V, NEKRASOV A.V, PETROV R.V
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine, infectious diseases. SUBSTANCE: vaccine represents the combination of antigens of opportunistic microorganisms with high-molecular synthetic carrier as N-hydroxy-1,4-ethylene piperazine and N-(carboxyethyl)-1,4-ethylene piperazinium bromide of molecular mass 30 000-120 000 Da with ratio antigens to carrier = 1:(5-50), respectively. The compound is represented as conjugate or prepared by complex-formation reaction. Invention can be used for prophylaxis and treatment of patients with suppurative-septic diseases. EFFECT: enhanced immunogenicity of vaccine. 4 cl, 3 dwg, 3 tbl, 5 ex