STABLE COMPOSITION WITH ANTI-INFLAMMATORY EFFECT

FIELD: medicine, pulmonology, allergy, pharmacy. SUBSTANCE: invention proposes composition for treatment of lung inflammatory diseases, among them, bronchial asthma. The composition comprising budesonide and water contains additionally propylene glycol, polyethylene oxide, succinic acid, Trilon B, n...

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Bibliographische Detailangaben
Hauptverfasser:	TROFIMOV N.A, PAVLOV V.M, ORLOV A.E, GIREVA N.N, SKACHILOVA S.JA, CHUCHALIN A.G, GARKAVAJA T.N
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine, pulmonology, allergy, pharmacy. SUBSTANCE: invention proposes composition for treatment of lung inflammatory diseases, among them, bronchial asthma. The composition comprising budesonide and water contains additionally propylene glycol, polyethylene oxide, succinic acid, Trilon B, nipagin in the following ratio of components, wt.-%: budesonide, 0.01-0.1; propylene glycol, 10.0-25.0; polyethylene oxide, 30.0-40.0; succinic acid, 0.05-0.5; Trilon B, 0.01-0.1; nipagin, 0.01-0.1; water up to 100.0. The composition can comprise additionally 6-(acetylamino)-hexanoic acid taken in the amount from 0.0% to 5% and polyethylene oxide-400 as polyethylene oxide. The composition can be used for inhalation. EFFECT: enhanced stability, reduced toxicity of composition. 4 cl