PIPERAZINE COMPOUND, INHIBITOR OF PRODUCTION OF TNF (TUMOR NECROSIS FACTOR)-alpha AND/OR PROMOTER OF INDUCTION OF IL-10 (INTERLEUKIN-10) AND AGENT FOR PROPHYLAXIS OR TREATMENT BASED ON THEREOF

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes piperazine compound of the general formula (I) alpha or its pharmaceutically acceptable salt where and R1 are similar or different and each mean hydrogen atom, halogen atom, lower alkyl, amino-group, amino-group substituted with monosubstituted lower acyl, nitro-group; R2 are similar or different and each means hydrogen atom, halogen atom, lower alkyl, lower alkoxy-group, nitro-group, hydroxy- -group, amino-group mono- or disubstituted with group taken among group including lower alkyl or lower acyl; R3, R4, R5 and R6 are similar or different and each means hydrogen atom, acyl; R7 and R8 are similar or different and each means hydrogen atom or lower alkyl; Y means formula: R9 where and R10 mean hydrogen atom; R11 and R12 are similar or different and each means hydrogen atom or lower alkyl; or R13 and R12 form in common alkylene; R13 and R14 mean hydrogen atom; m is a whole number 0-2; n is a whole number 0-2 and R15; cycle A means phenyl, pyrimidinyl, thiazolyl, pyridyl, pyrazolyl or imidazolyl. Invention describes also inhibitor of production of TNF-0